Author Julia Donaldson and illustrator Axel Scheffler created the panels as a "light-hearted" way of spreading the message.
They feature The Gruffalo, Stickman and The Smeds and The Smoos - all keeping a safe distance from one another.
The characters are also seen helping the vulnerable with their shopping.
As well as social distancing, the characters stress the importance of exercise and making video calls to their family members.
Donaldson hopes the images will emphasise best practices and help with home schooling, without being seen as "preaching".
While on lockdown, the author is also producing a weekly broadcast on the Gruffalo facebook page, reading stories, poems and singing songs.